Hepatitis: A Summary of NIH-Funded Research
April 7, 2012 • Posted in Fact Sheets and More
The 2008 research protocols listed below include studies that conduct invasive research on whole, living chimpanzees as well as those that use biological samples from chimpanzees (i.e. cells, tissues, blood, and/or serum.)
| Researcher: | ALTER, HARVEY J. |
| Grant No. | 1Z01CL002082-1308 |
| Project: | Studies of Viral Hepatitis and AIDS in the Chimpanzee Model |
| Institution: | NIH/Intramural |
| Project runs: | Grant first appeared in 1996; renewed yearly |
| Funding: | Unavailable |
| Researcher: | ALLEN, TODD M |
| Grant No. | 5U19AI066345-040005 |
| Project: | CD8 T Cell Selective Pressure and Hepatitis C Virus Sequence Evolution |
| Institution: | MASSACHUSETTS GENERAL HOSPITAL |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | ALLEN, TODD M |
| Grant No. | 5R01AI067926-03 |
| Project: | CD8 T Cell Selective Pressure and HCV Sequence Evolution |
| Institution: | MASSACHUSETTS GENERAL HOSPITAL |
| Project runs: | Aug. 15, 2006 – July 31, 2010 |
| Funding: | $517,856 ($169,784 for 2008) |
| Researcher: | RITOLA, KIMBERLY D. |
| Grant No. | 5F32DK080650-02 |
| Project: | Viral Dynamics of HCV Serine Protease Inhibitor Resistance |
| Institution: | ROCKEFELLER UNIVERSITY |
| Project runs: | Sept. 1, 2007 – Aug. 31, 2010 |
| Funding: | $100,924 ($51,278 for 2008) |
| Researcher: | LIANG, T. JAKE |
| Grant No. | 1Z01DK054504-1208 |
| Project: | Animal And Culture Models of Viral Hepatitis And Hepatocellular Carcinoma |
| Institution: | NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | LANFORD, ROBERT E. |
| Grant No. | 5R21AI067455-02 |
| Project: | Resolution of Acute Hepatitis B Virus Infections in Chimpanzees |
| Institution: | SOUTHWEST FOUNDATION FOR BIOMEDICAL RES |
| Project runs: | Mar. 1, 2007 – Feb. 28, 2010 |
| Funding: | $448,519 ($222,579 for 2008) |
| Researcher: | PURCELL, ROBERT H. |
| Grant No. | 1Z01AI001015-0208 |
| Project: | Pathogenesis of Parenteral Viral Hepatitis |
| Institution: | NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | PURCELL, ROBERT H. |
| Grant No. | 1Z01AI001016-0208 |
| Project: | New Approaches To Passive Immunoprophylaxis |
| Institution: | NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | PURCELL, ROBERT H. |
| Grant No. | 1Z01AI000823-1108 |
| Project: | New Approaches To Active Immunoprophylaxis |
| Institution: | NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | REHERMANN, BARBARA |
| Grant No. | 1Z01DK054508-1108 |
| Project: | Analysis and Modulation of Virus-Host Interaction in Animal Models |
| Institution: | NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | GRAKOUI, ARASH |
| Grant No. | 5R01AI070101-03 |
| Project: | Mechanisms of hepatitis C virus persistence |
| Institution: | EMORY UNIVERSITY |
| Project runs: | Sept. 1, 2006 – Aug. 31, 2011 |
| Funding: | $401,835 |
| Researcher: | PURCELL, ROBERT H. |
| Grant No. | 1Z01AI000311-2708 |
| Project: | Search For New and Emerging Etiologic Agents |
| Institution: | NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | WALKER, CHRISTOPHER M. |
| Grant No. | 5U19AI048231-090001 |
| Project: | HCV-Specific Cellular Immunity in Acute Hepatitis C |
| Institution: | RESEARCH INST NATIONWIDE CHILDREN’S HOSPITAL - COLUMBUS, OH |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | BHARDWAJ, NINA |
| Grant No. | 5R01AI061684-05 |
| Project: | Dendritic Cell mediated induction of Anti-HCV immunity |
| Institution: | NEW YORK UNIVERSITY SCHOOL OF MEDICINE |
| Project runs: | July 1, 2004 – June 30, 2009 |
| Funding: | $571,176 |
| Researcher: | WALKER, CHRISTOPHER M |
| Grant No. | 5R37AI047367-09 |
| Project: | HCV-specific T cell response |
| Institution: | RESEARCH INST NATIONWIDE CHILDREN’S HOSPITAL |
| Project runs: | Aug. 15, 1999 – Dec. 31, 2009 |
| Funding: | $541,702 |
| Researcher: | GALE, MICHAEL J. |
| Grant No. | 5U19AI040035-130004 |
| Project: | Innate Defenses that Control Hepatitis C Virus (HCV) |
| Institution: | UNIVERSITY OF TEXAS MEDICAL BR GALVESTON |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | LANFORD, ROBERT E. |
| Grant No. | 5U19AI040035-130002 |
| Project: | Virus-Host Interactions in Hepatitis C Virus (HCV) Infections |
| Institution: | UNIVERSITY OF TEXAS MEDICAL BR GALVESTON |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | RICE, CHARLES M. |
| Grant No. | 5U19AI040034-14 |
| Project: | Hepatitis C: Studies of Immunity and Pathogenesis |
| Institution: | ROCKEFELLER UNIVERSITY |
| Project runs: | Aug. 1, 1997 – June 30, 2010 |
| Funding: | $797,618 |
| Researcher: | WALKER, CHRISTOPHER M |
| Grant No. | 5U19AI048231-09 |
| Project: | HCV Replication and Immunity |
| Institution: | RESEARCH INST NATIONWIDE CHILDREN’S HOSPITAL |
| Project runs: | July 14, 2005 – June 30, 2010 |
| Funding: | $918,189 |
| Researcher: | LIANG, T. JAKE |
| Grant No. | 1Z01DK054503-1208 |
| Project: | Molecular Approaches To Vaccine Development For Hepatitis C |
| Institution: | NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | LIANG, T. JAKE |
| Grant No. | 1Z01DK054505-1208 |
| Project: | Mechanisms of Interferon Action and Resistance in Hepatitis C Virus Infection |
| Institution: | NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | ARNTZEN, CHARLES J |
| Grant No. | 5U19AI066332-04 |
| Project: | Plant-derived vaccines against hepatitis C Cooperative |
| Institution: | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS |
| Project runs: | Aug. 1, 2005 – July 31, 2010 |
| Funding: | $714,512 |
(The above project may involve primates other than chimpanzees.)
| Researcher: | CHISARI, FRANCIS V. |
| Grant No. | 2R01AI020001-25 |
| Project: | Pathogenesis of Liver Disease in Hepatitis |
| Institution: | SCRIPPS RESEARCH INSTITUTE - CA |
| Project runs: | July 1, 1983 – Dec. 31, 2012 |
| Funding: | $685,357 |
| Researcher: | DUBENSKY, THOMAS W |
| Grant No. | 5U01AI070834-04 |
| Project: | Development of Listeria-Based Clinical Consensus HCV Vaccine Candidates |
| Institution: | DUBENSKY, THOMAS W |
| Project runs: | Aug. 1, 2006 – July 31, 2009 |
| Funding: | $354,663 |
| Researcher: | EMERSON, SUZANNE U. |
| Grant No. | 1Z01AI000970-0308 |
| Project: | Molecular Studies of Hepatitis C Virus. |
| Institution: | NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | EXLEY, MARK A |
| Grant No. | 5R01DK066917-05 |
| Project: | Innate-like hepatic CD1d-reative NKT cells: Liver Disease |
| Institution: | BETH ISRAEL DEACONESS MEDICAL CENTER |
| Project runs: | Sept. 1, 2004 – July 31, 2009 |
| Funding: | $197,460 |
| Researcher: | FLOTTE, TERENCE R |
| Grant No. | 5P01DK058327-090002 |
| Project: | Liver-directed Gene Therapy for Alpha 1 Antitrypsin (AAT) Deficiency |
| Institution: | UNIVERSITY OF FLORIDA |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | JONES, CHRISTOPHER T |
| Grant No. | 5F32DK081193-02 |
| Project: | Characterization of the HCV p7 Protein |
| Institution: | ROCKEFELLER UNIVERSITY |
| Project runs: | Sept. 3, 2007 – Sept. 2, 2010 |
| Funding: | $52,898 |
| Researcher: | LEMON, STANLEY M |
| Grant No. | 5U19AI040035-13 |
| Project: | The Southeastern Cooperative Hepatitis C Research Group |
| Institution: | UNIVERSITY OF TEXAS MEDICAL BR GALVESTON |
| Project runs: | Aug. 1, 1997 – June 30, 2010 |
| Funding: | $1,414,039 |
| Researcher: | PURCELL, ROBERT H. |
| Grant No. | 1Z01AI000915-0708 |
| Project: | Pathogenesis Of Enteric Viral Hepatitis |
| Institution: | NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | ALTER, HARVEY |
| Grant No. | 1Z01CL002076-1308 |
| Project: | Evaluation Of Nucleic Acid Vaccine As A Preventive And Therapeutic Modality |
| Institution: | NIH (CLINICAL CENTER) |
| Project runs: | Unavailable |
| Funding: | Unavailable |
| Researcher: | NICOSIA, ALFREDO |
| Grant No. | 5U01AI070802-03 |
| Project: | Development of an Adenovirus based HCV Vaccine: preclinical safety and immunology |
| Institution: | OKAIROS, POMEZIA (RM) - Italy |
| Project runs: | Sept. 1, 2006 – Aug. 31, 2009 |
| Funding: | $180,033 |
| Researcher: | CHISARI, FRANCIS |
| Grant No. | 2R01CA076403-06A1 |
| Project: | Hepatitis C Virus Immunobiology and Pathogenesis |
| Institution: | Scripps Research Institute, La Jolla, CA |
| Project runs: | December 12, 1997 - May 31, 2008 |
| Funding: | $544,625 |
| Researcher: | CHISARI, FRANCIS |
| Grant No. | 1R01CA108304-01 |
| Project: | Cellular Genes that Control HCV Replication |
| Institution: | Scripps Research Institute, La Jolla, CA |
| Project runs: | December 19, 2003 - August 31, 2008 |
| Funding: | $403,153 |
| Researcher: | WALKER, CHRISTOPHER |
| Grant No. | 5R01AI060388-02 |
| Project: | AAV vectors for prevention and therapy of HCV infection |
| Institution: | Children’s Research Institute, Columbus, OH |
| Project runs: | September 29, 2003 - September 28, 2008 |
| Funding: | $408,128 |